submitted with permission by Marj Brooks
with thanks to Kevin & Donna Frizzell of DeSaix St. Bernards for generously allowing us to use many of their superb array of articles
DRUGS CONTRAINDICATED IN PREGNANCY
| Drug | Adverse Effects |
| Acetazolamide | Foetal Anomalies |
| Amphotericin B | Congenital Anomalies |
| Androgens | Masculinization of Fetus |
| Antineoplastics | Fetal Death or Anomalies |
| Bishydroxycoumarin | Fetal Death & Intrauterine Haemorrhage |
| Chloramphenicol | Foetal Death |
| Chlorpromazine | Neonatal Hepatic Necrosis |
| Cholinesterase Inhibitors | Neonatal Myasthenis |
| Corticosteroids | Cleft Palate |
| Diazoxide | Destruction of Foetal Islet Cells |
| Dimethylsulfoxide | Congenital Anomalies |
| EDTA | Congenital Anomalies |
| Estrogens | Feminization of Foetus |
| Ethoxyzolamide | Congenital Anomalies |
| Fluocytosine | Congenital Anomalies |
| Griseofulvin | Congenital Anomalies |
| Gold Salts | Congenital Anomalies |
| Indomethacin | Premature Closure of Ductus Arteriosus |
| lododeoxyuridine | Congenital Anomalies |
| Iodides | Fetal Goiter |
| Iodinated Casein | Neonatal Goiter |
| Isoniazid | Retarded Psychomotor Activity |
| Isoproterenol | Fetal Tachycardia |
| Lithium salts | Fetal Goiter |
| Meclizine | Congenital Anomalies |
| Meperidine | Inhibit Closure of Ductus Arteriosus |
| Mepivacaine | Fetal Bradycardia |
| Methoxamine | Placental Vasoconstriction & Foetal Hypoxia |
| Nitrofurantoin | Fetal Haemolysis |
| Paracetamol | Methemoglobinaemia |
| Phenylbutazone | Neonatal Goiter & Nephrosis |
| Phenylphrine | Placental Vasoconstriction – Foetal Hypoxia |
| Prochlorperazine | Congenital Anomalies |
| Propranolol | Foetal Bradycardia |
| Propylthiouracil | Neonatal Goiter |
| Quinine | Deafness and Thrombocytopenia |
| Reserpine | Respiratory Obstruction |
| Salicylates | Neonatal Bleeding |
| Sodium Selenites | Impaired Growth of Foetus |
| Streptomycin | Hearing Loss & Congenital Anomalies |
| S.R. Sulfonamides | Liver Atrophy and Hyperbilirubinemia |
| Tetracyclines | Impaired Bone and Tooth Development |
| Thiazides | Foetal Death and Thrombocytopenia |
| Vitamin A | Multiple Anomalies |
| Vitamin D | Hypercalcemia & Mental Retardation |
| Vitamin K Analogs | Hyperbilirubinemia |
| Warfarin | Intrauterine Haemorrhage |
DRUGS CONSIDERED TO BE SAFE DURING PREGNANCY
| Acetylcysteine | Disophenol | Morphine |
| Ammonium Chloride | Doxapram | Neomycin |
| Amoxicillin | Doxylamine | Niclosamide |
| Ampicillin | Enflurane | Nitrous Oxide |
| Atropine | Ephedrine | Oxytocin |
| Cephalexin | Erythromycin | Penicillin |
| Cephaloridine | Ethrane | Pentobarbital |
| Cephalothin | Furosemide | Phenobarbital |
| Chloramphenicol | Gentamicin | Pilocarpine |
| Chlorpheniramine | Glycopyrrolate | Piperazine |
| Chymotrypsin | Guaifenesin | Polymyxin B |
| Clindamycin | Halothane | Pralidoxime |
| Clonazepam | Heparin | Primidone |
| Codeine | Kanamycin | Procaine |
| Colistin | Ketamine | Pyrantel |
| Dextromethorphan | Lidocaine | Pyrilamine |
| Diazepam | Lincomycin | Salbutamol |
| Dichlorvos | Mannitol | Spironolactone |
| Dicloxacillin | Mebendazole | Sulfonamides |
| Diethylcarbamazine | Metaproterenol | Tetracaine |
| Diethyl Ether | Methapyrilene | Theophylline |
| Digitoxin | Methenamine | Thiopental |
| Digoxin | Methohexital | Tiletamine |
| Dimenhydrinate | Metronidazole | Triamterene |
| Diphenhydramine | Miconazole | Urokinase |
DRUGS NOT PROVEN TO BE SAFE FOR USE DURING
PREGNANCY BUT NOT NECESSARILY CONTRAINDICATED
| Acepromazine | Glycobiarsol | Procainamide |
| Aminopentamide | Hexylcaine | Prochlorperazine |
| Aminopromazine | Hydralazine | Promazine |
| Arsenamide | Hydrocortisone | Proparacaine |
| Aspirin | Iron Dextran | Propiopromazine |
| Bithionol | Lenperone | Pyrimethamine |
| Bunamidine | Levamisole | Quinacrine |
| Butorphanol | Liothyronine | Quinidine |
| N-Butyl Chloride | Meprobamate | Ronnel |
| Caffeine | Methocarbamol | Saffan |
| Chlorpromazine | Methoxyflurane | Spectinomycin |
| Chlorprothixene | Methylprednisolone | Stanozolol |
| Cimetidine | Neostigmine | Styrylpyridium |
| Colchicine | Nitroglycerine | Thiabendazole |
| Cortisone | Nitroprusside | Thyroxine |
| Cythioate | Nystatin | Toluene |
| Dapsone | Phenoxybenzamin | Trichlorfon |
| Dichlorophene| | Phthalofyne | Trifluomeprazine |
| Dithiazanine | Physostigmine | Trimethoprim |
| Dobutamine | Prazosin | Xylazine |